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CELLS OF CONNECTIVE TISSUE 9. Major functions of connective tissue include: 1) binding and supporting, 2) protecting, 3) insulating, 4) storing reserve fuel, and 5) transporting substances within the body. Fibroblasts secrete the precursors of all the components of the extracellular matrix, primarily the ground substance and a variety of fibers . Its main components are proteoglycans, glycosaminoglycans and multi-adhesive glycoproteins such as laminin, fibronectin and others. Connective Tissue Components Connective (supporting) tissue may be a voluminous, strong, yet elastic sort of tissue with significant physical body roles. This viscous liquid, much like raw egg whites in appearance and consistency, surrounds all the cells in the body, and is a part of the internal ocean. GROUND SUBSTANCE By Deane Juhan: A transparent fluid ground substance is found to one degree or another in all of the body's connective tissues, and it may be thought of as the basis for the production of all their other forms. 3. psychoactive substance . The main function of fibroblasts is to maintain the structural integrity of connective tissues by continuously secreting precursors of the extracellular matrix. The ground substance is composed of an organic substance (usually a protein) and an inorganic substance (usually a mineral or water). Ground substance. See more. The matrix or the ground substance of the connective is a viscous and gel-like substance containing much water content. The ground substance is an aqueous gel of glycoproteins and proteoglycans that occupies the space between cellular and fibrillar elements of the connective tissue. Proteoglycans provide the firmness of the ground substance. Together the ground substance and fibers make up the extracellular matrix. Components Cells Fixed Fibroblasts Adipocytes Persistent mesenchymal cells Wandering Macrophage Mast cells Plasma cells Pigment cells Eosinophil Neutrophil Matrix Ground substance Proteoglycans GAG /MPS SO4 Non SO4 Fibers Collagen Elastic Reticular CONNECTIVE TISSUE 8. The ground substance secreted by a fibroblast has a lot to do with the type of connective tissue it produces, too. Bone, cartilage, fat, and blood are all special forms of connective tissue. The ground substance fills all of the spaces among the cells and fibers. 2. the material constituting an organ or body. ground substance: [ sub´stans ] 1. physical material that has form and weight; called also matter . Adipose tissue is a lipid-storing type of loose connective tissue.Also called fat tissue, adipose is composed primarily of adipose cells or adipocytes. Connective tissue fibers and matrix are synthesized by specialized cells called fibroblasts. The ground substance acts as a fluid matrix that suspends the cells and fibers within the particular connective tissue type. Hyaluronic sulfate and chondroitin sulfate are two examples. While adipose tissue can be found in a number of places in the body, it is found primarily beneath the skin.Adipose is also located between muscles and around internal organs, particularly those in the abdominal cavity. It is characterized by a gel-like viscous consistency and is polyanionic. Connective tissue is classified into two subtypes: soft and specialized connective tissue. Classification. Ground substance definition, the homogeneous substance in which the fibers and cells of connective tissue are embedded. Ground substance may be fluid, gel, or solid, and, except for blood, is secreted by the cells of the connective tissue: Cell adhesion proteins hold the connective tissue together. 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